Pressure (mechanical) effects in infrared tissue ablation - art. no. 685410
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Publication Details
Output type: Other
Author list: Edwards G, Wagner W, Sokolow A, Pearlstein R
Publisher: Society of Photo-optical Instrumentation Engineers
Publication year: 2008
Volume number: 6854
Start page: 85410
End page: 85410
Number of pages: 1
ISBN: 978-0-8194-7029-4
ISSN: 0277-786X
eISSN: 1996-756X
Languages: English-Great Britain (EN-GB)
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Open access status: closed
Abstract
We experimentally demonstrate that the acoustic transients propagating as a result Free-Electron Laser (FEL) ablation in brain tissue exhibit a strong FEL wavelength dependence. These acoustic transients were measured with a time-resolved, polarization quadrature laser interferometer. The transients are multiphased, with displacements of tens of microns and durations of tens of milliseconds. We calculated the Fourier transforms, power spectra, and pressure transients based on these displacement data sets. For 3.0 mu m irradiation, the bandwidth of the Fourier components extends to similar to 20 kHz, while for 6.45 mu m irradiation the bandwidth of the Fourier components extend to similar to 8 kHz. For the 3.0 mu m irradiation, the power spectra indicate acoustic energy propagates in the bandwidth up to similar to 12 kHz, with structure in the 1-4 kHz range. For the 6.45 mu m radiation, the mechanical power spectra indicate the acoustic energy propagates in the bandwidth up to similar to 7 kHz, with structure throughout. The pressure transients resulting from 3.0 mu m irradiation have a leading phase with a faster onset, shorter duration, and more than ten times the peak pressure compared to that observed in pressure transients resulting from 6.45 mu m irradiation. For 3.0 mu m irradiation, the observed pressure transients have peak pressures in the MPa range and durations of similar to 1 ms, while for 6.45 mu m irradiation the pressure transients have peak pressures in the 0.1 MPa range and durations of about similar to 3 ms.
Keywords
interferometry, mechanical effects, tissue ablation
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