Systemic lupus erythematosus: association with psoralen--ultraviolet-A treatment of psoriasis.
Authors / Editors
Research Areas
No matching items found.
Publication Details
Output type: Journal article
Author list: Eyanson, Greist, Brandt, Skinner
Publisher: AMA American Medical Association
Publication year: 1979
Volume number: 115
Issue number: 1
Start page: 54
End page: 6
Number of pages: -47
ISSN: 0003-987X
Languages: English-Great Britain (EN-GB)
Unpaywall Data
Open access status: closed
Abstract
Systemic lupus erythematosus (SLE) developed in as 23-year-old woman with psoriasis during treatment with psoralen-ultraviolet-A (PUVA). The connective tissue disease was characterized by an erythematous rash, hair loss, nephritis, splenomegaly, seizures, and coma. Serum antinuclear antibodies were present in high titer, and hypocomplementemia developed. Antibodies to native or ultraviolet-irradiated DNA were not demonstrated. While the association of psoriasis and lupus may have been fortuitous, the temporal relationships suggest that PUVA treatment in this case may have been of pathogenetic importance in the development of the connective tissue disease.
Keywords
No matching items found.
Documents
No matching items found.
