The protective effects of taurine on experimental acute pancreatitis in a rat model

Authors / Editors

Akgul, Erik

Research Areas

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Publication Details

Output type: Journal article

Author list: Akay C, Yaman H, Oztosun M, Cakir E, Yildirim AO, Eyi YE, Agilli M, Akgul EO, Aydin I, Kaldirim U, Tuncer SK, Eken A, Oztas E, Poyrazoglu Y, Yasar M, Ozkan Y

Publisher: SAGE Publications

Publication year: 2013

Journal: Human and Experimental Toxicology (0960-3271)

Volume number: 32

Issue number: 5

Start page: 522

End page: 529

Number of pages: 8

ISSN: 0960-3271

eISSN: 1477-0903

Languages: English-Great Britain (EN-GB)

Unpaywall Data

Open access status: closed

Abstract

These results showed that Tau reduces lipid peroxidation, amylase and MPO activities and the concentrations of proinflammatory cytokines secondary to AP and also increases superoxide dismutase and glutathione peroxidase activities in rats with sodium taurocholate-induced AP. It also has a marked ameliorative effect at histopathologic lesions. With these effects, Tau protects the cells from oxidative damage, reduces inflammation and promotes regression of pancreatic damage.

Keywords

experimental acute pancreatitis, inflammation, oxidative stress, rat, Taurine

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