Bilateral deafness and unilateral facial nerve palsy as presenting features of Wegener's granulomatosis - A case report
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Publication Details
Output type: Journal article
Author list: Bohne S, Koscielny S, Burmeister HP, Guntinas-Lichius O, Wittekindt C
Publisher: Springer
Publication year: 2010
Journal: HNO (0017-6192)
Volume number: 58
Issue number: 5
Start page: 480
End page: 483
Number of pages: 4
ISSN: 0017-6192
eISSN: 1433-0458
Languages: German-Germany (DE-DE)
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Open access status: closed
Abstract
A 72-year-old female patient presented with otitis of her left ear with inner ear depletion. Despite administration of intravenous antibiotics according to the resistogram and mastoidectomy the patient developed a similar pathological condition in the right ear and facial nerve palsy on the left side. Treatment with trimethoprim/sulfamethoxazole under the working diagnosis of a localised seronegative Wegener's granulomatosis was initiated without achieving remission. Cyclophosphamide pulse therapy in combination with high-dose methylprednisolone was initiated with rapid cure of the bilateral otitis. Sensorineural hearing loss and facial nerve palsy remained irreversible.
Keywords
Cochlear implant, Facial nerve palsy, Otitis, Seronegativity, Wegener's granulomatosis
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