The impact of obesity on risk factors and prevalence and prognosis of coronary heart disease-the obesity paradox

Authors/Editors

Lavie, Cahil

Research Areas

No matching items found.

Publication Details

Output type: Journal article

Author list: De Schutter A., Lavie C., Milani R.

Publisher: Elsevier

Publication year: 2014

Journal: Progress in Cardiovascular Diseases (0033-0620)

Volume number: 56

Issue number: 4

Start page: 401

End page: 408

Number of pages: 8

ISSN: 0033-0620

eISSN: 1873-1740

URL: http://api.elsevier.com/content/abstract/scopus_id:84892432214

Unpaywall Data

Open access status: closed

Abstract

Obesity is associated with a host of cardiovascular risk factors and its prevalence is rising rapidly. Despite strong evidence that obesity predisposes to the development and progression of coronary heart disease (CHD), numerous studies have shown an inverse relationship between various measures of obesity (most commonly body mass index) and outcomes in established CHD. In this article we review the evidence surrounding the < obesity paradox. ≫ in the secondary care of CHD patients and the CHD presentations where a paradox has been found. Finally we discuss the impact of cardiorespiratory fitness and a number of mechanisms which may offer potential explanations for this puzzling phenomenon. © 2014 Elsevier Inc.

Keywords

Coronary heart disease, Obesity, Obesity paradox

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